Table 1. Baseline characteristics of the patients of included studies.
Study | Number of patients | Mean age | Male | BMI | HTN | DM | Previous AF | CRF | COPD | Mean LVEF | Mean LAD | β-blockers | ACEI/ARB | Statins | Amiodarone | Valve surgery | Off-pump surgery |
years | % | kg/m2 | % | % | % | % | % | % | mm | % | % | % | % | % | % | ||
Calo 2005 | 160 | 65.5 | 85.0 | NR | 80.0 | 32.5 | 0 | 9.4 | 16.3 | 55.8 | 39.7 | 57.5 | 79.4 | 56.9 | 0 | 0 | 11.9 |
Heidt 2009 | 102 | 66.4 | 68.6 | NR | NR | NR | 0 | NR | NR | 52.2 | 40.3 | NR | NR | NR | 0 | 0 | NR |
Saravanan 2010 | 103 | 66.0 | 79.6 | 27.8 | 32.0 | 14.6 | 0 | 6.8 | 8.7 | NR | NR | 85.4 | 83.5 | 98.1 | 0 | 0 | 0 |
Heidarsdottir 2010 | 168 | 67.0 | 79.4 | 27.4 | 63.1 | 15.1 | 0 | NR | NR | 60 | NR | 76.2 | NR | NR | 0 | 25.6 | 11.9 |
Farquharson 2011 | 194 | 64.0 | 73.2 | 30.5 | 77.5 | 31.4 | 0 | NR | 10.8 | 64.5 | NR | 41.2 | 56.7 | 73 | 0 | 37.1 | 0.5 |
Sorice 2011a 1 | 93 | 63.5 | 84.9 | NR | 66.7 | 39.8 | 0 | 7.5 | 33.3 | 53 | 41.5 | 59.1 | 51.6 | 62.3 | 0 | 0 | 100 |
Sorice 2011b 1 | 108 | 63.0 | 78.7 | NR | 62.0 | 44.4 | 0 | 3.7 | 33.3 | 52.1 | 39.9 | 61.1 | 58.3 | 68.5 | 0 | 0 | 0 |
Sandesara 2012 | 243 | 62.7 | 80.7 | NR | 88.5 | 36.2 | NR | 2.1 | 14.4 | 52.7 | 39 | 79.8 | 50.6 | 74.1 | 0 | 11.5 | 25.1 |
Mozaffarian 2012 | 1516 | 63.7 | 72.2 | 28.3 | 75.6 | 26.0 | 7.8 | 6.4 | 11.3 | 56.7 | 42.2 | 57.9 | 51.2 | 56.9 | 3.9 | 49.9 | 11.6 |
The study by Sorice et al includes two randomized comparisons in patients who underwent off-pump or on-pump surgery. These two sets of data were analyzed separately in the meta-analysis, as Sorice 2011a and Sorice 2011b.
BMI, body mass index; HTN, hypertension; DM, diabetes mellitus; AF, atrial fibrillation; CRF, chronic renal failure; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; LAD, left atrial dimension; ACEI, angiotensin converting enzyme inhibitors; ARB, angiotensin II receptor blockers; NR, not reported.