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. 2013 Sep 10;8(9):e74742. doi: 10.1371/journal.pone.0074742

Figure 1. Effect of HCA and ZnPP on HO-1 protein expression and activity in lung tissue.

Figure 1

Western blot and densitometry analysis were used for HO-1 protein expression (A). The induction of HO-1 protein by ischemia-reperfusion (IR) was accompanied by a marked increase in HO-1 activity (B). HCA further enhanced HO-1 protein expression and activity. ZnPP completely abolished HO-1 activity in either the absence or presence of HCA, although ZnPP also increased HO-1 protein expression. A representative blot is shown. Data are expressed as mean ± SD. *P < 0.05, ***P < 0.001, compared with control; + P < 0.05, compared with IR-vehicle; # P < 0.05, compared with IR+HCA, using one-way ANOVA with Bonferroni post-test.