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The PAP increased significantly in the ischemia-reperfusion (IR) group. The increase in the PAP was attenuated significantly by treatment with HCA, but not when ZnPP was added. Data are expressed as mean ± SD. +significantly different from IR-vehicle (P < 0.05); # significantly different from IR+HCA (P < 0.05), using two-way ANOVA with Bonferroni post-test.
