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. Author manuscript; available in PMC: 2014 Oct 10.
Published in final edited form as: Neuroscience. 2013 Jul 3;250:151–165. doi: 10.1016/j.neuroscience.2013.06.057

Figure 9.

Figure 9

Loss of NK-1R-ir neurons in the RVM decreased hyperalgesia produced by prolonged inflammation. A) Mechanical paw withdrawal threshold; B) Paw withdrawal response frequencies to mechanical stimuli; and C) Paw withdrawal latencies to heat before (0) and up to 4 days following CFA in animals pretreated with Blank-SAP and SSP-SAP. ##p< 0.001 refers to differences from before CFA (day 0); *p < 0.05, **p < 0.01, ***p < 0.001 indicate differences between groups at corresponding days after CFA.