Fig. 5.
Auditory phenotype of +/dfwi5 by backcross generation. Auditory sensitivity of +/dfwi5 individuals in N3 (open circles, solid line, n = 3), N4 (open circles, large dashed line, n = 6) and N5 (open circles, small dashed line, n = 5) was similar. A shift in phenotype occurred at N6 (open squares, dashed line, n = 9) where sensitivity improved at several frequencies and was stable through N10 (open squares, solid line, n = 13). Wild-type controls (inverted black triangles, n = 30) were not statistically different by generation and are grouped for clarity. See Supplemental Table 1 for statistical analysis. Error bars represent SEM.