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Back-scattering interferometry for (a) AR-PR:pepstatin + 1F1, (b) apo-PR + 1F1, (c) AR- PR:pepstatin + 1F1-N, and (d) apo-PR + 1F1-N. Note that all Kd values are equal within experimental error, but the phase change is significantly greater for compound binding to apo-PR.
