Figure 10.
C57/BL6 Nramp1G169 mice have significantly greater increases in proinflammatory serum cytokine concentrations and decreases in anti-inflammatory serum cytokine concentrations than Sv129S6 mice 3 weeks following Salmonella enterica serovar Typhimurium infection. Concentration of serum cytokines as indicated above each graph. Data shown are from 5 controls (both strains), 10 S. Typhimurium–infected Sv129S6 (Sv129) mice (white bars), and 9 C57/BL6 Nramp1G169 (B6-N1R) (black bars). C, control; CXCL-1, chemokine (C-X-C motif) ligand 1; IFN-γ, interferon-γ; IL, interleukin; Inf, infected; MCP-1, monocyte chemotactic protein–1; TNF-α, tumor necrosis factor–α.