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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Nucl Med Biol. 2013 Jul 29;40(7):912–918. doi: 10.1016/j.nucmedbio.2013.06.007

Table 2.

Comparison of log D and free fraction in plasma for [11C]BA, [11C]VPA [11C]PBA.

Radioligands M.W. Log D at pH 7.4 % unbound in plasma
[11C]BA 88.1 1.02±0.08 (n=3) 82±0.4 (n=2)
[11C]PBA 164.2 −0.20±0.03 (n=6) 1.5±0.7 (n=6)
[11C]VPA 144.2 0.26±0.03 (n=5) 26±0.3 (n=2)