Table 2.
Radioligands | M.W. | Log D at pH 7.4 | % unbound in plasma |
---|---|---|---|
[11C]BA | 88.1 | 1.02±0.08 (n=3) | 82±0.4 (n=2) |
[11C]PBA | 164.2 | −0.20±0.03 (n=6) | 1.5±0.7 (n=6) |
[11C]VPA | 144.2 | 0.26±0.03 (n=5) | 26±0.3 (n=2) |
Radioligands | M.W. | Log D at pH 7.4 | % unbound in plasma |
---|---|---|---|
[11C]BA | 88.1 | 1.02±0.08 (n=3) | 82±0.4 (n=2) |
[11C]PBA | 164.2 | −0.20±0.03 (n=6) | 1.5±0.7 (n=6) |
[11C]VPA | 144.2 | 0.26±0.03 (n=5) | 26±0.3 (n=2) |