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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Mol Cancer Ther. 2013 Jul 3;12(9):1738–1748. doi: 10.1158/1535-7163.MCT-13-0049-T

Figure 3. #220–324 had minimal effects in PTPN11 knockout cells.

Figure 3

PTPN11 knockout (PTPN11Fl/Fl/Ad-Cre+) and WT (PTPN11+/+/Ad-Cre+) MEFs were cultured in DMEM with 10% FBS and #220–324 at the indicated concentrations for 72 hrs (A) or at 20 μM for the indicated periods of time (B). DMSO-treated cells were included as negative controls. Cell numbers were determined using the One Solution Cell Proliferation Assay kit. Experiments were performed twice with similar results. Data shown are mean±S.E.M. from one experiment.