Table 3.
Main agents used as empiric antibiotic therapy and definitive treatment in the two groups of patients with postoperative peritonitis following conventional and bariatric surgery expressed as number and proportions
| Empiric therapy | Definitive therapy | |||
|---|---|---|---|---|
| Conventional surgery (n = 134) | Bariatric surgery (n = 49) | Conventional surgery (n = 134) | Bariatric surgery (n = 49) | |
| Monotherapy | 37 (28) | 6 (12)a | 42 (31) | 21 (43) |
| Combination therapy | ||||
| Amoxicillin/clavulanic acid | 3 (2) | 1 (2) | 20 (15) | 19 (39)b |
| Piperacillin tazobactam | 79 (59) | 34 (69) | 37 (28) | 17 (35) |
| Imipenem/cilastatin | 38 (28) | 11 (22) | 41 (31) | 5 (10)b |
| Third-generation cephalosporins | 2 (1) | – | 12 (9) | –a |
| Vancomycin | 50 (37) | 19 (39) | 39 (29) | 19 (39)a |
| Aminoglycosides | 58 (43) | 31 (63)a | 18 (13) | 6 (12) |
| Fluoroquinolones | 11 (8) | 2 (4) | 12 (9) | 2 (4) |
| Metronidazole | 6 (4) | 2 (4) | 25 (19) | 3 (6)a |
| Fluconazole | 39 (29) | 23 (47)a | 41 (31) | 19 (39) |
aOverall comparison of conventional surgery and bariatric surgery, p < 0.05
bOverall comparison of conventional surgery and bariatric surgery, p < 0.01