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Individual indinavir (A) AUC(0,12 h) and (B) C12 h for HIV-infected pregnant women using 400/100 mg twice daily during the second and third trimesters of pregnancy and post-partum. Dashed line represents (A) the 10th percentile AUC (12.9 μg ml−1 h) in non-pregnant historical patients and (B) suggested minimum target trough concentration (0.1 μg ml−1)
