Table 2.

Characteristics of Studies Included in Meta-Analysis

Study Number	Total patients	Mean Age	Male/Female	Genotype 1 / 2 / 3 / 4
1	33	54	24/9	0 / 17 /5 / 4
2	168	36.7	79/89	57 / 17 /20 / 71
3	54	34.4	31/23	20 /0 /0/ 34
4	161	29.5	68/93	68 / 15/14 / 64
5	34	39	19/11 #	25 / 0 /0/ 0
6	27	31.7	20/7	9 / 1 /11/ 0
7	46	32.8	26/20	22 / 10/ 9 / 4
8	16	29	12/4	9 / 1 / 6 / 0
9	23	26.6	15/8	12 / 2 / 6 / 3
10	44	34.6	20/24	17 / - / - / 2
11	60	35.5	25/35	36 / 3/ 11/ 2
12	12	39.5	3/9	7 / - / 3 / 0
13	44	36	19/25	27 / -/ - / 0
14	28	35	23/5	6 / 7/ 3 / 0
15	89	34	56/33	59 / 3 / 17 / 1
16	8	33	4/4	4 / 1 / 3 / 0
17	67	42	47/20	42 / 22 / 0 / 0
18	14	31.2	3/11	0 / 14 / 0 / 0
19	6	65.8	6/0	6 / 0 / 0 / 0
20	40	40	23/17	21 / 11/ 3 / 2
21	34	30	27/7	16 / 3 / 12 / 0
22	67	31	35/32	42 / 9 / 7 / 0
Total	1075	36.4 +/−8.7	585/486	505/ 136/ 130 /187

NA= Not available. # = Gender unknown in four patients