Table I.
Patient Demographics (n = 28)
| Mean (Number of Patients) | Standard Deviation | Range | |
|---|---|---|---|
| Age, y | 12.5 (28) | 5.3 | 2.1–20.2 |
| Age group, y | |||
| ≥2 and <6 | 3.5 (6) | 1.5 | 2.1–5.3 |
| ≥6 and <12 | 9.5 (2) | - | 8.3, 10.6 |
| ≥12 to 18 | 15.5 (20) | 2.0 | 12.3–20.2a |
| Height, cm | 140.5 (28) | 30.5 | 81.2–175.8 |
| Weight, kg | 44.8 (28) | 26.2 | 10.3–106.4 |
| Pharmacokinetic/pharmacodynamic evaluation day (days after transplant) | |||
| Early posttransplant | 2.4 (27) | 1.3 | 1–5 |
| Prior to discharge | 7.0 (25) | 3.0 | 3–17 |
| Stable period | 193 (19) | 138 | 81–611 |
| Creatinine clearance (mL/min per 1.73 m3) | |||
| Early posttransplant | 102 (27) | 67 | 14–243 |
| Prior to discharge | 116 (25) | 48 | 21–228 |
| Stable period | 100 (19) | 36 | 63–223 |
| Number of Patients | |||
| Gender (female/male) | 11/17 | ||
| Race (African American/ white) | 4/24 | ||
| Ethnicity (Hispanic/ non-Hispanic) | 2/26 | ||
| Donor type (living/cadaver) | 17/11 | ||
Parameter values are reported as means with standard deviations (SD) and ranges. Creatinine clearance (CrCL) was estimated with the Schwartz equation.30
a
One patient >18 years with developmental delay, both physically and mentally, was accepted for enrollment.