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BCA2 promotes breast cancer cell proliferation partially through downregulating the expression of p21. MCF-7 and T47D cells were transiently transfected with siLuc, sip21, and siBCA2 siRNA, as indicated. Cell lysates were collected 72 hours later and subjected to WB analysis. Protein levels of p21 and BCA2 in MCF-7 (A) or T47D (B) were shown. The cell viability was measured by the SRB assay and shown in the graphs, respectively, (A) MCF-7 or (B) T47D (**P < .01).
