Table 1.
Current screening methods and guidelines for colorectal cancer
Method | Sensitivity | Interval | Society |
Fecal tests | |||
FOBT | Yearly | USPSTF, ASGE, | |
USMSTF | |||
FIT | 65.8%[32,33] | Yearly | |
Fecal DNA | 50%-60%[34] | Unspecified | USMSTF |
Serum markers | |||
CEA | 30%[35] | ||
CA19-9 | |||
Imaging tests | |||
DCBE | 85%-97%[36] | Every 5 years | USMSTF |
CTC | 55%-94%[37] | Every 5 years | USMSTF |
Optical tests | |||
FS | Every 5 years | USPSTF, ASGE, USMSTF | |
Every 10 years | |||
FC | USPSTF, ASGE, USMSTF |
FOBT: Fecal occult blood test; FIT: Fecal immunochemical based stool tests; CEA: Carcinoembryonic antigen; DCBE: Double-contrast barium enema; CTC: Computed tomography colonography; FS: Flexible sigmoidoscopy; FC: Flexible colonoscopy; USPSTF: United States Preventive Services Task Force; ASGE: American Society for Gastrointestinal Endoscopy; USMSTF: Multi-Society Task Force on Colorectal Cancer.