Table 2.
Analysis of the treated nodules according to the type of transcatheter arterial chemoembolization (per nodule analysis) n (%)
| Variable | All treated nodules 63 in 38 patients |
Type of TACE |
P value | |
| DEB-TACE 38 in 22 patients | c-TACE 25 in 16 patients | |||
| Degree of necrosis | 54.3% ± 41.2% | 55.7% ± 41.9% | 52.2% ± 40.9% | 0.7420 |
| Complete necrosis (100%) | 21 (33.3) | 14 (36.8) | 7 (28.0) | 0.5877 |
| Histological response | 0.2834 | |||
| Appropriate (necrosis ≥ 90%) | 25 (39.7) | 17 (44.7) | 8 (32.0) | |
| Partial (50% < necrosis < 90%) | 9 (14.3) | 3 (7.9) | 6 (24.0) | |
| Inadequate (necrosis ≤ 50%) | 29 (46.0) | 18 (47.4) | 11 (44.0) | |
| Diameters of nodules (cm) | 2 (0.7-10) | 1.8 (0.7-4.5) | 2.2 (1-10) | 0.1752 |
| Number of nodules | 0.2492 | |||
| Single | 17 (27.0) | 8 (21.1) | 9 (36.0) | |
| Degree of necrosis | 63.1% ± 37.8% | 69.7% ± 34.8% | 57.2% ± 41.5% | 0.5144 |
| Multiple | 46 (73.0) | 30 (78.9) | 16 (64.0) | |
| Degree of necrosis | 51.1% ± 42.3% | 52.0% ± 43.4% | 49.4% ± 41.7% | 0.8454 |
| Modality of TACE | 0.3015 | |||
| Superselective | 34 (54.0) | 23 (60.5) | 11 (44.0) | |
| Degree of necrosis | 73.9% ± 34.3% | 76.2% ± 33.8% | 69.1% ± 36.5% | 0.5803 |
| Non-superselective | 29 (46.0) | 15 (39.5%) | 14 (56.0) | |
| Degree of necrosis | 31.3% ± 37.0% | 24.3% ± 33.3% | 38.9% ± 40.5% | 0.2970 |
Analysis performed considering nodules reached by transarterial treatment (targeted lesions). Continuous variables are reported as median and range or mean and standard deviation and compared using the Student’s t test or Mann-Whitney U test as appropriate. TACE: Transcatheter arterial chemoembolization; DEB: Doxorubicin-eluting bead; c-TACE: Conventional TACE.