Table 3.
Effect of G-197A polymorphism on gastric cancer development n (%)
| GA + AA | GG | OR | 95%CI | P-value2 | |
| Age | |||||
| < 50 yr | 18 (17.1) | 4 (7.1) | 2.7 | 0.8-8.4 | 0.09 |
| ≥ 50 yr | 87 (82.9) | 52 (92.9) | |||
| Gender | |||||
| Male | 51 (48.6) | 21 (37.5) | 1.6 | 0.8-3.05 | 0.19 |
| Female | 54 (51.4) | 35 (62.5) | |||
| H. pylori+ | 65 (61.9) | 33 (58.9) | 0.88 | 0.45-1.71 | 0.74 |
| H. pylori- | 40 (38.1) | 23 (41.1) | |||
| TNM stage1 | |||||
| I-II | 22 (55) | 6 (16.2) | 6.3 | 2.2-18.5 | 0.001 |
| III-IV | 18 (45) | 31 (83.8) | |||
| Tumor differentiation | |||||
| Well | 25 (23.8) | 9 (16.1) | 1.003 | ||
| Moderate | 57 (54.3) | 35 (62.5) | 0.56 | 0.24-1.34 | 0.19 |
| Poor | 23 (21.9) | 12 (21.4) | 0.66 | 0.23-1.86 | 0.43 |
1
Data presented for 77 patients;
2
All comparisons between categorical variables were made using a two-sided χ2 test;
3
Used as reference for tumor differentiation analyses. Values in parentheses indicate the percentage. H. pylori: Helicobacter pylori; TNM: Tumor, node, metastasis.