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. 1970 Oct;20(4):583–586. doi: 10.1128/am.20.4.583-586.1970

Microbiological Assay for Estimating Salivary Concentrations of the Cariostatic Antibiotic Actinobolin

D E Hunt 1, E L Bradley Jr 1, Joan W Bachmann 1
PMCID: PMC376993  PMID: 5498607

Abstract

A logarithmic-ratio microbiological assay has been developed for the estimation of concentrations of actinobolin (or inhibitory equivalents) in human saliva. The utility of this assay has been demonstrated by presenting data that show concentrations of this antibiotic (or inhibitory equivalents) detected in saliva or saline after incubation at 37 C for periods as long as 6 hr. The results of some statistical analyses of the assay data have been included.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hunt D. E., Caldwell R. C. Use of fast green in agar-diffusion microbiological assays. Appl Microbiol. 1969 Dec;18(6):1098–1099. doi: 10.1128/am.18.6.1098-1099.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hunt D. E., Pittillo R. F. Antifungal action of 1,3-bis(2-chloroethyl)-1-nitrosourea. Antimicrob Agents Chemother (Bethesda) 1965;5:710–716. [PubMed] [Google Scholar]
  3. Hunt D. E., Sandham H. J., Caldwell R. C. In vitro antibiotic sensitivity of oral microorganisms to actinobolin. J Dent Res. 1970 Jan-Feb;49(1):137–139. doi: 10.1177/00220345700490010601. [DOI] [PubMed] [Google Scholar]
  4. JORDAN H. V., FITZGERALD R. J., BOWLER A. E. Inhibition of experimental caries by sodium metabisulfite and its effect on the growth and metabolism of selected bacteria. J Dent Res. 1960 Jan-Feb;39:116–123. doi: 10.1177/00220345600390010501. [DOI] [PubMed] [Google Scholar]
  5. Jablon J. M., Zinner D. D. Differentiation of cariogenic streptococci by fluorescent antibody. J Bacteriol. 1966 Dec;92(6):1590–1596. doi: 10.1128/jb.92.6.1590-1596.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. PITTILLO R. F., SCHABEL F. M., Jr, QUINNELLY B. G. Studies on the antimicrobial nature of action of actinobolin. Antibiot Chemother (Northfield) 1961 Aug;11:501–511. [PubMed] [Google Scholar]

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