Table 2.
Substrate scope of pyrroloindoline formation.
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Determined by 1H NMR analysis of crude reaction mixture. Values in parentheses are dr obtained using acrylate 6 and catalyst 7.
Determined by SFC using chiral stationary phase. Values in parentheses are ee obtained using acrylate 6 and catalyst 7.
Isolated yield of exo-diastereomer.
1.6 equiv SnCl4 was employed.