Table 4.
Genotype frequency distribution of two SNPs of TNFA promoter in patients and controls.
| SNP | Genotype | Genotypic frequency in patients | Genotypic frequency in controls | P value | OR (95% CI) |
|---|---|---|---|---|---|
| rs361525 (−238 G/A) | GG | 0.81 | 0.833 | 0.567 | 0.855 (0.533–1.370) |
| GA | 0.175 | 0.16 | 0.712 | 1.120 (0.619–1.818) | |
| AA | 0.015 | 0.007 | 0.686 | 1.932 (0.302–15.301) | |
|
| |||||
| rs1800629 (−308 G/A) | GG | 0.918 | 0.911 | 0.876 | 1.099 (0.572–2.112) |
| GA | 0.078 | 0.089 | 0.753 | 0.865 (0.447–1.673) | |
| AA | 0.004 | 0 | — | — | |