Fig. 1.

Frequency of detection of HDL-associated proteins in MS-based proteomic studies. By our count, there are currently 14 published studies that have used soft-ionization MS techniques on human plasma HDL in which an effort has been made to separate them from nonlipid-containing proteins. Proteins that have appeared in at least three of the studies (from different laboratories) are shown. The bar represents the number of studies in which the protein was observed. Although not quantitative by any means, proteins that are more frequently observed likely reflect the most abundant species in HDL.