TABLE 3.
Best-fit volumetric analysis of HDL subspecies
Circulating HDL Subspecies | ||||||
Stoichiometry |
Diameter |
Monolayer Thickness | ||||
Object | Origin | Lipid (PC:CE:UC:TG) | Apo (A-I:A-II) | NDGGE (Å) | Calculated (Å) | Calculated (Å) |
HDL[1] | Immunoaffinity | 18:15:4:4 | 2:0 | 76.4 ± 0.8 | 66.6-72.2 | 12.4 |
HDL[2] | Immunoaffinity | 24:20:6:5 | 2:1 | 78.2 ± 0.8 | 72.4-78.0 | 13.6 |
HDL[3] | Immunoaffinity | 40:25:7:7 | 2:2 | 81.0 ± 0.9 | 77.3-82.9 | 14.6 |
HDL[4] | Immunoaffinity | 41:34:9:7 | 3:0 | 85.0 ± 1.2 | 79.6-85.2 | 13.9 |
HDL[5] | Immunoaffinity | 67:55:17:13 | 3:1 | 89.9 ± 2.4 | 88.5-94.5 | 14.6 |
HDL[6] | Immunoaffinity | 78:66:17:13 | 3:2 | 95.3 ± 2.5 | 93.4-99.0 | 15.4 |
HDL[7] | Immunoaffinity | 133:114:43:19 | 4:0 | 108.5 ± 3.8 | 104.0-109.6 | 15.3 |