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Elongation of EPA by rat Elovl5 containing amino acid point mutations Elovl5 W231C (A), Elovl5 Y233I (B), Elovl5 S218L (C), Elovl5 C219S (D), or Elovl5 G220A (E). Values represent the means ± SD of triplicate incubations. Values with different symbols are significantly different from each other. The inserts show the Elovl5 amino acid sequence of TMD6, TMD7, and the extracellular loop in blue with the Elovl2 amino acid point mutation in red.
