TABLE 3.
Dog | Guinea-pig | Hamster | Human | Mouse (Balb/c) | Mouse (C57BL/6) | Rat (Han Wistar) | Rat (Sprague-Dawley) | |
7-oxoLCA | 41 ± 83 | 13593 ± 5482 | 11 ± 9 | 3 ± 1 | 20 ± 12 | 6 ± 4 | 4 ± 5 | 22 ± 28 |
7-oxoLC-Tau | 9 ± 11 | 3 ± 2 | 3 ± 1 | 1 ± 0.1 | 8 ± 2 | 32 ± 14 | 2 ± 0.2 | 4 ± 1 |
7-oxoLC-Gly | 1 ± 0.2 | 5481 ± 3557 | 1 ± 1 | 1 ± 0.1 | 5 ± 3 | ND | ND | 1 ± 2 |
The results are expressed in nM as mean ± SD (n = 8). Underlined values represent below lower limit of quantification. ND, not detected.