TABLE 4.
Logistic regression of lipid classes and subclasses with sex and smoking status
| Lipid Class or Subclassa | Sex | Smoking status | ||||
| IQR Odds Ratio (95% CI)b | c | Difference, %d | IQR Odds Ratio (95% CI)e | c | Difference, %f | |
| dhCer | 0.88 (0.74–1.05) | 1.87E-01 | −8.7 | 0.96 (0.80–1.17) | 7.93E-01 | −4.0 |
| Cer | 1.62 (1.35–1.95)g | 2.21E-06 | 6.9 | 0.96 (0.79–1.17) | 7.93E-01 | 0.5 |
| MHC | 1.05 (0.88–1.25) | 6.22E-01 | 2.7 | 1.03 (0.85–1.26) | 8.01E-01 | 1.1 |
| DHC | 0.80 (0.67–0.96) | 2.67E-02 | −1.9 | 1.01 (0.83–1.24) | 9.06E-01 | −0.4 |
| THC | 0.59 (0.49–0.70) | 1.34E-07 | −5.7 | 1.18 (0.97–1.42) | 2.14E-01 | 0.9 |
| GM | 1.57 (1.31–1.89) | 4.78E-06 | 9.1 | 1.11 (0.91–1.35) | 3.94E-01 | 3.5 |
| SM | 0.56 (0.45–0.68) | 1.34E-07 | −7.1 | 0.78 (0.63–0.97) | 8.79E-02 | −4.4 |
| PC | 0.92 (0.76–1.11) | 4.10E-01 | −1.1 | 1.18 (0.96–1.46) | 2.14E-01 | 0.9 |
| PC(O) | 1.16 (0.97–1.39) | 1.45E-01 | 1.7 | 0.76 (0.61–0.93) | 6.02E-02 | −2.9 |
| PC(P) | 1.05 (0.89–1.24) | 6.22E-01 | 1.1 | 0.75 (0.62–0.91) | 4.97E-02 | −3.9 |
| LPC | 1.78 (1.49–2.13) | 1.46E-08 | 14.1 | 1.09 (0.90–1.31) | 4.98E-01 | 4.9 |
| LPC(O) | 1.37 (1.15–1.64) | 1.28E-03 | 10.3 | 1.22 (1.00–1.48) | 1.54E-01 | 6.4 |
| PE | 0.76 (0.63–0.92) | 8.58E-03 | −8.8 | 1.25 (1.02–1.54) | 1.04E-01 | 1.8 |
| PE(O) | 0.86 (0.73–1.02) | 1.04E-01 | −4.4 | 0.86 (0.71–1.05) | 2.14E-01 | −4.5 |
| PE(P) | 1.36 (1.14–1.62) | 1.28E-03 | 4.6 | 0.75 (0.61–0.91) | 4.97E-02 | −5.3 |
| LPE | 1.35 (1.14–1.60) | 1.16E-03 | 9.4 | 1.23 (1.03–1.46) | 8.82E-02 | 6.4 |
| PI | 0.84 (0.70–1.02) | 9.56E-02 | −3.5 | 1.13 (0.92–1.39) | 3.54E-01 | 0.6 |
| PS | 0.74 (0.63–0.88) | 1.16E-03 | −16.6 | 0.86 (0.72–1.04) | 2.14E-01 | −11.9 |
| PG | 1.30 (1.10–1.54) | 4.58E-03 | 7.9 | 1.26 (1.06–1.50) | 7.57E-02 | 9.1 |
| CE | 1.57 (1.32–1.88) | 2.38E-06 | 6.9 | 1.16 (0.96–1.40) | 2.14E-01 | 4.0 |
| COH | 1.00 (0.84–1.19) | 9.30E-01 | −0.6 | 1.01 (0.83–1.23) | 9.06E-01 | −0.4 |
| DG | 1.52 (1.29–1.79) | 2.56E-06 | 14.6 | 1.12 (0.95–1.32) | 2.97E-01 | 7.0 |
| TG | 1.55 (1.31–1.83) | 1.97E-06 | 12.8 | 1.18 (0.99–1.40) | 1.87E-01 | 8.3 |
a
Sum of the individual species within each class or subclass.
b
Interquartile range (IQR) odds ratio, adjusted for age, BMI, SBP, 2 h post load glucose, and smoking status.
c
Benjamini and Hochberg corrected. Bold type indicates P < 0.05.
d
Male relative to female.
e
Interquartile range odds ratio, adjusted for sex, age, BMI, SBP and 2 hr post load glucose.
f
Current smokers relative to nonsmokers.
g
An individual with a 75th percentile level of Cer is 1.62 times more likely to be male than an individual with a 25th percentile level of Cer.