Table 5. Coagulation Assays Among Maternal Factor V Leiden Mutation Carriers and Noncarriers in the First and Second or the Third Trimesters.
| FVL Carriers |
FVL Noncarriers |
|||
|---|---|---|---|---|
| Assay | Trimester 1&2 (n = 79) |
Trimester 3 (n = 43) |
Trimester 1&2 (n = 132) |
Trimester 3 (n = 126) |
| Antithrombin III activity | 103.6 (7.7) | 105.4 (7.4) | 103.0 (8.2) | 105.5 (8.2) |
| Protein C activity | 118.0 (20.3) | 113.5 (24.0) | 118.7(24.1) | 108.4 (24.3) |
| Protein C antigen | 110.1 (17.8) | 111.9 (22.3) | 110.2 (18.3) | 106.3 (19.9) |
| Protein S activity | 44.5 (11.3) | 36.6 (8.8) | 50.4 (13.6) | 41.7(13.2) |
| Protein S total antigen | 98.0 (16.8) | 100.5 (19.6) | 98.8 (19.2) | 94.0 (19.7) |
| Protein S free antigen | 61.7(14.0) | 51.2 (10.4) | 60.6 (14.0) | 52.3 (14.0) |
FVL, factor V Leiden mutation.
Data are presented as mean (SD).