TABLE 3.
CaD adherence at AV2 (1 Year Post-CaD Randomization), Initial Change Model
| Effect | Logistic regression model of CaD first-year adherence > 80% |
||
|---|---|---|---|
| p | Odds ratio | 95% Confidence limits | |
| Sociodemographic variables | |||
| Age group | |||
| 50–55 vs. 70–79 | < .001 | 0.82 | 0.73–0.92 |
| 55–60 vs. 70–79 | .438 | 0.96 | 0.87–1.06 |
| 60–65 vs. 70–79 | .309 | 1.05 | 0.95–1.16 |
| 65–70 vs. 70–79 | .021 | 1.12 | 1.02–1.24 |
| Race or ethnicity | |||
| African American vs. white | < .001 | 0.62 | 0.55–0.70 |
| Hispanic vs. white | .052 | 0.84 | 0.71–1.00 |
| Others or unknown vs. white | .091 | 0.86 | 0.72–1.03 |
| College or higher vs. high school or less | .084 | 1.06 | 0.99–1.12 |
| Had medical insurance | |||
| Yes vs. no | .019 | 1.18 | 1.03–1.35 |
| Married or with partner vs. divorced, separated, widowed, or single | < .001 | 1.12 | 1.06–1.20 |
| Prior history of CVD | |||
| Yes vs. no | .349 | 0.96 | 0.89–1.04 |
| Prior history of cancer | |||
| Yes vs. no | .495 | 1.05 | 0.91–1.21 |
| Diabetes | |||
| Yes vs. no | .019 | 1.17 | 1.03–1.33 |
| High risk (≥ 4) of osteoporosis | |||
| Yes vs. no | .652 | 0.98 | 0.92–1.06 |
| Family history of breast cancer or colorectal cancer or MI | |||
| Yes vs. no | .298 | 1.03 | 0.97–1.10 |
| Shortened CES-D/DIS ≥ .06 | |||
| Yes vs. no | .013 | 0.88 | 0.80–0.97 |
| Had > 3 life events | |||
| Yes vs. no | .162 | 0.95 | 0.89–1.02 |
| Emotion expressiveness > 3 | |||
| Yes vs. no | .031 | 0.88 | 0.79–0.99 |
| Optimism ≥ 19 | |||
| Yes vs. no | .825 | 1.01 | 0.91–1.13 |
| Hostility ≥ 8 | |||
| Yes vs. no | .521 | 0.97 | 0.88–1.07 |
| On any special diet at baseline | |||
| Yes vs. no | .976 | 1.00 | 0.94–1.06 |
| Total expenditure from physical act ≥ 11 | |||
| Yes vs. no | .024 | 1.07 | 1.01–1.14 |
| Current smoker vs. never or former smoker | |||
| Yes vs. no | < .001 | 0.77 | 0.69–0.86 |
| Current drinker vs. past or nondrinker | |||
| Yes vs. no | .06 | 0.94 | 0.88–1.00 |
| Take any supplement at AV1 | |||
| Yes vs. no | < .001 | 1.24 | 1.16–1.33 |
| Taking any medication at AV1 | |||
| Yes vs. no | .231 | 1.05 | 0.97–1.13 |
| Take calcium supplement at AV1 | |||
| Yes vs. no | < .001 | 1.17 | 1.08–1.27 |
| Psychosocial variables | |||
| Social support ≥ 25 | |||
| Yes vs. no | .81 | 0.99 | 0.89–1.10 |
| Social strain ≥ 5 | |||
| Yes vs. no | .617 | 0.98 | 0.92–1.05 |
| Caregiving burden | |||
| Yes vs. no | .552 | 1.02 | 0.96–1.08 |
| Treatment factors | |||
| Total number of GI symptoms at baseline | |||
| 1 vs. none | .003 | 0.89 | 0.82–0.96 |
| 2 vs. none | < .001 | 0.78 | 0.72–0.85 |
| 3 vs. none | < .001 | 0.76 | 0.68–0.84 |
| Had 4-week contact | |||
| Yes vs. no | < .001 | 1.37 | 1.27–1.48 |
| Contact type 6 months after CaD randomization | |||
| Visit vs. phone or mail | < .001 | 2.09 | 1.92–2.27 |
| CaD 1st-year pill type | |||
| Chew vs. swallow | < .001 | 0.72 | 0.67–0.77 |
| Mix vs. swallow | < .001 | 0.49 | 0.45–0.53 |
| 1st-year DM adherence | |||
| Adherent in DM vs. not in DM | .004 | 1.17 | 1.05–1.31 |
| Not adherent in DM vs. not in DM | .707 | 1.02 | 0.93–1.11 |
| 1st-year HT adherence | |||
| < 80% vs. not in HT | .06 | 0.87 | 0.75–1.01 |
| ≥ 80% vs. not in HT | < .001 | 1.66 | 1.53–1.81 |
| Change clinic from CaD randomization to CaD1 | |||
| Yes vs. no | .17 | 0.69 | 0.40–1.18 |
Note. Max-rescaled R2 = 0.11; AV1 = annual visit 1; C statistics = 0.670; Hosmer-Lemeshow goodnessof-fit test p = .3118. BMI = body mass index; CED-D/DIS = Center for Epidemiological Studies Depression Scale; CaD = calcium and vitamin D clinical trial; CVD = cardiovascular disease; DM = dietary modification; HT = hormone treatment.