Figure 2. Hazard ratio estimates and 95% confidence intervals from univariable (A) and multivariable (B) Cox proportional hazards models.

Hazard ratios for continuous predictors represent an interquartile difference (HR_IQR, described in the Methods section) to aid interpretation and facilitate comparisons across variables. Cho = choline; CI = confidence interval; Cr = creatine; mI = myo-inositol; NAA = N-acetylaspartate; TIV = total intracranial volume; WM = white matter; WMH = white matter hyperintensity volume.