Table 1.
Pro-survival BH protein expression frequencies in human NB tumor tissue microarray
| Mcl1 | Bcl2 | Mcl1 or Bcl2 | Mcl1 and Bcl2 | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n (%) |
present (%) |
p* | high (%) |
p | present (%) |
p | high (%) |
p | present (%) |
p | high (%) |
p | present (%) |
p | high (%) |
p | ||
| All | 165 | 42/134 | 18/134 | 48/154 | 24/154 | 78/138 | 36/132 | 14/128 | 6/128 | |||||||||
| (31) | (13) | (31) | (16) | (57) | (27) | (11) | (5) | |||||||||||
| Risk Group | H | 35 | 10/24 | 1.0 | 5/24 | 0.54 | 16/32 | 0.02 | 9/32 | 0.16 | 21/26 | 0.05 | 12/26 | 0.08 | 5/24 | 0.29 | 2/24 | 0.63 |
| (N = 101) | (35) | (42) | (21) | (50) | (28) | (81) | (46) | (21) | (8) | |||||||||
| IL | 66 | 24/58 | 9/58 | 16/63 | 9/63 | 34/59 | 15/58 | 6/57 | 3/57 | |||||||||
| (66) | (41) | (16) | (25) | (14) | (58) | (26) | (11) | (5) | ||||||||||
| MYCN Amp | Y | 17 | 5/10 | 0.15 | 4/10 | 0.03 | 6/14 | 0.56 | 3/14 | 0.72 | 8/11 | 0.21 | 6/11 | 0.07 | 3/10 | 0.15 | 1/10 | 0.48 |
| (N = 103) | (17) | (50) | (40) | (43) | (21) | (73) | (55) | (30) | (10) | |||||||||
| N | 86 | 20/75 | 8/75 | 29/84 | 15/84 | 40/78 | 19/77 | 9/74 | 4/74 | |||||||||
| (83) | (27) | (11) | (35) | (18) | (51) | (25) | (12) | (5) | ||||||||||
*
Fisher’s exact test.