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. Author manuscript; available in PMC: 2013 Sep 11.
Published in final edited form as: J Am Coll Cardiol. 2010 May 11;55(19):2140–2147. doi: 10.1016/j.jacc.2010.01.031

Table 3.

Mortality and Cardiovascular Morbidity in the Healthy Normal Subgroup (n = 703) During 10 Years of Follow-Up According to Baseline NT-proBNP

Outcome (No. of Events) HR (95% CI) per 1 SD
Increase in Log Variable
p Value HR (95% CI) for Values
Above 80th Percentile
p Value
Death (19)
 Unadjusted model 1.52 (0.88–2.62) 0.132 0.72 (0.17–3.09) 0.655
 Age-, sex-, BMI-adjusted 0.95 (0.47–1.92) 0.881 1.06 (0.24–4.74) 0.938
Heart failure (13)
 Unadjusted model 1.21 (0.63–2.35) 0.564 1.19 (0.26–5.38) 0.819
 Age-, sex-, BMI-adjusted 1.36 (0.61–3.01) 0.452 1.69 (0.36–7.96) 0.507
Myocardial infarction (14)
 Unadjusted model 0.71 (0.40–1.28) 0.255 0.45 (0.06–3.39) 0.435
 Age-, sex-, BMI-adjusted 0.72 (0.33–1.59) 0.421 0.66 (0.08–5.23) 0.697
Cerebrovascular accident (38)
 Unadjusted model 1.06 (0.74–1.52) 0.738 0.61 (0.22–1.73) 0.356
 Age-, sex-, BMI-adjusted 0.79 (0.49–1.26) 0.320 1.06 (0.37–3.05) 0.915
Combined end point (72)
 Unadjusted model 1.04 (0.79–1.37) 0.765 0.76 (0.36–1.57) 0.454
 Age-, sex-, BMI-adjusted 0.93 (0.65–1.33) 0.688 1.14 (0.53–2.42) 0.736

CI = confidence interval; HR = hazard ratio; NT-proBNP = N-terminal pro–B-type natriuretic peptide; other abbreviations as in Table 1.