Table 3.
Mortality and Cardiovascular Morbidity in the Healthy Normal Subgroup (n = 703) During 10 Years of Follow-Up According to Baseline NT-proBNP
Outcome (No. of Events) | HR (95% CI) per 1 SD Increase in Log Variable |
p Value | HR (95% CI) for Values Above 80th Percentile |
p Value |
---|---|---|---|---|
Death (19) | ||||
Unadjusted model | 1.52 (0.88–2.62) | 0.132 | 0.72 (0.17–3.09) | 0.655 |
Age-, sex-, BMI-adjusted | 0.95 (0.47–1.92) | 0.881 | 1.06 (0.24–4.74) | 0.938 |
Heart failure (13) | ||||
Unadjusted model | 1.21 (0.63–2.35) | 0.564 | 1.19 (0.26–5.38) | 0.819 |
Age-, sex-, BMI-adjusted | 1.36 (0.61–3.01) | 0.452 | 1.69 (0.36–7.96) | 0.507 |
Myocardial infarction (14) | ||||
Unadjusted model | 0.71 (0.40–1.28) | 0.255 | 0.45 (0.06–3.39) | 0.435 |
Age-, sex-, BMI-adjusted | 0.72 (0.33–1.59) | 0.421 | 0.66 (0.08–5.23) | 0.697 |
Cerebrovascular accident (38) | ||||
Unadjusted model | 1.06 (0.74–1.52) | 0.738 | 0.61 (0.22–1.73) | 0.356 |
Age-, sex-, BMI-adjusted | 0.79 (0.49–1.26) | 0.320 | 1.06 (0.37–3.05) | 0.915 |
Combined end point (72) | ||||
Unadjusted model | 1.04 (0.79–1.37) | 0.765 | 0.76 (0.36–1.57) | 0.454 |
Age-, sex-, BMI-adjusted | 0.93 (0.65–1.33) | 0.688 | 1.14 (0.53–2.42) | 0.736 |
CI = confidence interval; HR = hazard ratio; NT-proBNP = N-terminal pro–B-type natriuretic peptide; other abbreviations as in Table 1.