Table 1.
Number of animals used for the different experiments
| Analyses | Young (0.6–8 yrs) |
Middle age (9–17 yrs) |
Old (>19 yrs) |
|---|---|---|---|
| Liver mtDNA lesions and mtDNA abundance |
12 | 6 | 3 |
| Liver glutathione peroxidase activity | 5 | 4 | 3 |
| Liver total SOD activity | 5 | 2 | 4 |
| Liver catalase activity | 5 | 3 | 3 |
| Liver lipid peroxidation | 5 | 4 | 4 |
| Liver protein carbonylations | 7 | 6 | 2 |
| Liver APE1 and MnSOD expression | 7 | 6 | 2 |
| Liver histology | 5 | 3 | 3 |
| PBMCs mtDNA lesions | 11 | 10 | 4 |
| PBMCs APE1 and MnSOD expression | 5 | 2 | 4 |
| PBMCs protein carbonylations | 5 | 2 | 4 |