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. Author manuscript; available in PMC: 2013 Sep 11.
Published in final edited form as: Xenotransplantation. 2012 Jan-Feb;19(1):56–63. doi: 10.1111/j.1399-3089.2011.00691.x

Fig. 2.

Fig. 2

(A) The proliferative response of human CD4+ T cells (n = 3) to WT and GTKO porcine aortic endothelial cells (pAECs) before and after activation by pIFN-γ (left), where the response was significantly less to GTKO pAECs before (P < 0.001) and after (P < 0.01) activation. Additionally, MLRs were harvested on three consecutive days (4, 5, and 6) where CD4+ T-cell proliferation was consistently lower in response to GTKO pAECs. 3H incorporation values are presented as counts per minute (CPM). Data represent the mean (±SEM) and are representative of three different experiments. (B) The proliferative response of human CD8+ T cells (n = 3) to WT and GTKO pAECs before and after activation by pIFN-γ (left), where the response was significantly less to GTKO pAECs before (P < 0.001) and after (P < 0.05) activation. Additionally, MLRs were harvested on three consecutive days (4, 5, and 6) where CD8+ T-cell proliferation was consistently lower in response to GTKO pAECs. 3H incorporation values are presented as CPM. Data represent the mean (±SEM) and are representative of three different experiments.