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. 2013 Aug 2;20(10):1404–1414. doi: 10.1038/cdd.2013.96

Figure 3.

Figure 3

Wound contraction. (a) Delayed contraction was observed when mice were aged 30 weeks in both the WT and AKO groups; ***P<0.005 versus WT (young) and AKO (young). (b) A HFD resulted in delayed wound contraction only in the AKO mice; *P<0.05 versus WT (old), WT (old—high fat) and AKO (old). (c) GzmB deficiency improves wound contraction in HFD-fed AKO mice; ***P<0.005 versus WT (old – high fat), #P<0.01 versus AKO (old – high fat). (d) No significant differences in α-SMA staining were observed between genotypes when fed a HFD. P-values were calculated using two-way repeated measures ANOVA (a–c) and Kruskal–Wallis test with Dunn's multiple comparison post test (d)