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Improvement on the subscale scores of the Impact on Dry Eye in Everyday Life questionnaire, from baseline (with habitual drops) to visit 4 (after 4 weeks of treatment with study drops). (A) Mean change per patient; maximum possible change was 100 units. (B) Clinical significance of improvement (effect size indices).Notes: Error bars represent the standard deviation and are shown unidirectional for clarity. *P < 0.01; **P < 0.001.
