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Chemical structure of voclosporin; 11 amino acid residues are numbered in a clockwise direction: (4R)-4-[(E)-2-butenyl]-4,N-dimethyl-L-threoneine (MeBmt), α-amino butyric acid (Abu), methylglycine (MeGly), N-methylleucine (MeLeu), valine (Val), MeLeu, L-alanine (Ala), D-alanine (D-Ala), MeLeu, MeLeu, N-methylvaline (MeVal).
