Table 6.
Average number of hydrogen bonds formed by the functional groups of model polymers with voclosporin
# | Model name | Backbone | Side chain | Total | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
NH | Length Å(Å) |
C1=O | Length Å(Å) |
C2= O | Length Å(Å) |
*C4-O- C5-O- |
C3=O | Length (Å) |
|||
1 | pc13-0-0 | 1.0 | 1.97 | - | - | - | - | - | - | - | 1.0 |
2 | pc12-2-0-ch4 | 1.6 | 2.08 | 0.4 | 2.45 | - | - | - | 0.7 | 2.22 | 2.7 |
2 | pc12-2-0-ch4prp | 0.8 | 1.94 | 0.8 | 2.11 | 0.1b | - | - | 0.8 | 2.31 | 2.5 |
4 | pc9-2-2-ch4 | 1.1 | 2.09 | - | - | 0.9 | 2.22 | - | - | - | 2.0 |
10 | pc10-2-2-ch4 | - | - | - | - | - | - | 0.4a | - | - | 0.4 |
14 | pc12-1-1-ch2 | 0.4 | 2.04 | 0.9 | 2.10 | 0.6 | 2.24 | - | - | - | 1.9 |
17 | pc11-1-1-ch2 | 0.9 | 1.89 | - | - | 0.8 | 2.21 | - | - | - | 1.7 |
C4 represents all carbons of the repeat motif of PEG1K
Weak hydrogen bonds of 2.30 and 2.39 (Å), respectively