Table 1. Association of clinicopathologic characteristics with Ang-2 or VEGFR-3 expression and survival in 112 OSCC patients.
| Clinicopathologic characteristic | n | Ang-2 expression | VEGFR-3 expression | Log-rank test | ||
| n (%) | P1 | n (%) | P1 | P* | ||
| Age, years | 0.252 | 0.127 | 0.287 | |||
| ≥56 | 48 | 27 (56.3) | 26 (54.2) | |||
| <56 | 64 | 29 (45.3) | 28 (43.8) | |||
| Gender | 0.526 | 0.291 | 0.372 | |||
| Female | 31 | 17 (54.8) | 13 (41.9) | |||
| Male | 81 | 39 (48.1) | 43 (53.1) | |||
| Lesion site | 1.000 | 0.484 | 0.295 | |||
| Other | 76 | 38 (50.0) | 35 (46.1) | |||
| Tongue | 36 | 18 (50.0) | 16 (44.4) | |||
| Smoking | 0.477 | 0.751 | 0.298 | |||
| Never | 67 | 35 (52.2) | 33 (49.3) | |||
| Ever | 42 | 19 (45.2) | 22 (52.4) | |||
| Missing | 3 | |||||
| Alcohol | 0.366 | 1.000 | 0.713 | |||
| Never | 56 | 34 (60.7) | 28 (50.0) | |||
| Ever | 50 | 26 (52.0) | 25 (50.0) | |||
| Missing | 6 | |||||
| Differentiation | 0.563 | 0.847 | 0.016 | |||
| High | 67 | 32 (47.8) | 33 (49.3) | |||
| Poor/moderate | 45 | 24 (53.3) | 23 (51.1) | |||
| TNM stage | 0.186 | 0.850 | 0.135 | |||
| I or II | 57 | 32 (56.1) | 28 (49.1) | |||
| III or IV | 55 | 24 (43.6) | 28 (50.9) | |||
| Lymph node metastasis | 0.088 | 0.000 | 0.008 | |||
| Absent | 61 | 26 (42.6) | 21 (34.4) | |||
| Present | 51 | 30 (58.8) | 35 (68.6) | |||
P1: chi-square test and *P: log-rank test.