Table 2. Total nasal deposition (% nebulizer output) and maxillary sinus deposition (% total nasal deposition) assessed without and with lead mask (LM) shielding after pulsating aerosol application and anterior gamma camera imaging in healthy volunteers and in chronic rhinosinusitis patients (CRS) before and after sinus surgery (FESS).
| Total nasal deposition (% output) | Maxillary sinus deposition (% nasal dose) | Maxillary sinus deposition (LM shield) (% nasal dose) | |
|---|---|---|---|
| Healthy volunteers | |||
| Mean +/- SD | 61.3+/-8.6 | 7.1+/-1.7 | 5.7+/-1.9 |
| Median (min, max) | 59.3 (47.9, 75.2) | 6.2 (5.0, 10.3) | 5.8 (3.1, 9.4) |
| CRS before FESS | |||
| Mean +/- SD | 56.7+/-13.3 | 4.0+/-1.7** | 3.7+/-2.5* |
| Median (min, max) | 56.3 (36.1, 77.0) | 3.6 (1.8, 7.6) | 3.5 (0.8, 8.2) |
| CRS after FESS | |||
| Mean +/- SD | 46.7+/-12.7**,+ | 6.1+/-2.2++ | 4.9+/-2.9++ |
| Median (min, max) | 44.8 (25.1, 65.4) | 5.5 (3.1, 10.1) | 4.0 (1.2, 8.8) |
*= p < 0.05 and **= p < 0.01: compared to healthy volunteers; += p < 0.05 and ++= p < 0.01: CRS before to after FESS.