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. 2013 Sep 11;8(9):e73030. doi: 10.1371/journal.pone.0073030

Table 2. Comparison of progression and non-progression in patients with BAD and LD.

BAD LD
Progression Non-progression P Progression Non-progression P
N = 75 N = 104 N = 14 N = 115
Age, mean±SD 64.31±13.32 62.58±11.29 0.363 68.50±12.71 65.43±12.21 0.379
Gender, male, n (%) 46(61.3) 75(72.1) 0.128 10(71.4) 76(66.1) 0.920
CRP, median (IQR), mg/L 2.9(1.7–8.4) 2.11(0.90–5.28) 0.025* 2.95(1.68–7) 2.7(1.26–5.2) 0.552
Hcy, mean±SD, umol/L 15.90±7.00 13.15±4.74 0.004** 15.75±6.17 16.14±8.73 0.872
Hypertension, n (%) 65(86.7) 91(87.5) 0.869 12(85.7) 104(90.4) 0.933
Dyslipidemia, n (%) 63(84.0) 91(87.5) 0.505 9(64.3) 94(81.7) 0.156
Diabetes mellitus, n (%) 37(49.3) 40(38.4) 0.147 6(42.9) 43(37.4) 0.691
Smoking, n (%) 23(30.7) 33(31.7) 0.880 3(21.4) 38(33.0) 0.564
Ischemic heart disease, n (%) 27(36.0) 32(30.8) 0.463 8(57.1) 48(41.7) 0.272

BAD, branch atheromatous disease; LD, lipohyalinotic degeneration; CRP, C-reactive protein; Hcy, Homocysteine; IQR, interquartile range; Progression, defined as worsening by ≥ 1 point in the NIHSS for motor function during the first 5 days.

*

P<0.05.

**

P<0.01.