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. 2013 Sep 11;8(9):e75218. doi: 10.1371/journal.pone.0075218

Table 3. Attitudes to costs in medical treatment as explicators for estimates deviating from actual price (n=740).

Physician’s estimate deviated from actual price by ≥50%
Simvastatin OR (95% CI) Alendronate OR (95% CI) Infliximab OR (95% CI) Natalizumab OR (95% CI) Escitalopram OR (95% CI)
I consider the cost to society when deciding whether or not to initiate an intervention* 1.0 (0.7-1.5) 1.1 (0.7-1.6) 0.8 (0.5-1.2) 0.6 (0.4-1.0)* 1.0 (0.7-1.4)
I can reduce my referral and prescribing costs without compromising my patients’ health 0.8 (0.5-1.3) 0.4 (0.2-0.6)** 1.4 (0.9-2.3) 1.6 (0.8-3.2) 0.9 (0.6-1.5)
Willing to pay more than 405 to give the patient his/her preferred treatment; injection vs. pill§ 1.4 (0.9-2.2) 1.6 (1.0-2.4)* 0.7 (0.5-1.0) 1.2 (0.7-2.1) 1.2 (0.8-1.8)
Estimate of escitalopram (Cipralex) differed from actual price by ≥50%* 1.5 (1.0-2.2)* 2.2 (1.5-3.3)* 1.0 (0.7-1.4) 1.9 (1.2-3.0)** __

Variable names with an asterisk are part of the basic model. Odds ratios with two asterisks indicate significance at the 1% level and those with one asterisk at 5%. Attitude measurement coding: 1 = agree, 0 = disagree. OR > 1 if physicians who agreed with the statement were more likely to deviate from accurate prices than others; OR <1 if they were less likely to deviate.

§

Explanation provided: injection avoids the trouble of taking the pills every week. Pills cause mild nausea when taken (once a week). In addition the injection is 10% more effective in increasing bone mass than the tablets.