Table 2. Characteristics of SUD* and No SUD subgroups of the MI Cohort (N = 7,876).
| SUD* (N = 203) | No SUD*(N = 7,673) | p-value | ||
| Age≥65 | 74 (36.5%) | 3,876 (50.5%) | <0.001 | |
| Male | 170 (83.7%) | 5,352 (69.8%) | <0.001 | |
| Elixhauser comorbidities ** | Congestive heart failure | 55 (27.1%) | 1,676 (21.8%) | 0.075 |
| Cardiac arrhythmias | 31 (15.3%) | 1,377 (18.0%) | 0.326 | |
| Valvular disease | 22 (10.8%) | 714 (9.3%) | 0.459 | |
| Pulmonary circulation disorders | 5 (2.5%) | 112 (1.5%) | 0.243 | |
| Peripheral vascular disease | 15 (7.4%) | 498 (6.5%) | 0.609 | |
| Hypertension uncomplicated | 77 (37.9%) | 2,941 (38.3%) | 0.908 | |
| Hypertension complicated | 0 (0.0%) | 9 (0.1%) | 1.000† | |
| Paralysis | 0 (0.0%) | 40 (0.5%) | 1.000† | |
| Other neurological disorders | 17 (8.4%) | 228 (3.0%) | <0.001 | |
| Chronic pulmonary disease | 36 (17.7%) | 807 (10.5%) | 0.001 | |
| Diabetes uncomplicated | 30 (14.8%) | 1,255 (16.4%) | 0.548 | |
| Diabetes complicated | 6 (3.0%) | 258 (3.4%) | 0.751 | |
| Hypothyroidism | 12 (5.9%) | 505 (6.6%) | 0.704 | |
| Renal failure | 12 (5.9%) | 316 (4.1%) | 0.207 | |
| Liver disease | 13 (6.4%) | 14 (0.2%) | <0.001† | |
| Peptic ulcer disease | 12 (5.9%) | 219 (2.9%) | 0.011 | |
| AIDS | 0 (0.0%) | 0 (0.0%) | - | |
| Lymphoma | 0 (0.0%) | 17 (0.2%) | 1.000† | |
| Metastatic cancer | 0 (0.0%) | 34 (0.4%) | 1.000† | |
| Solid tumor without metastasis | 5 (2.5%) | 382 (5.0%) | 0.102 | |
| Rheumatoid arthritis/collagen vascular diseases | 2 (1.0%) | 147 (1.9%) | 0.595 | |
| Coagulopathy | 11 (5.4%) | 114 (1.5%) | <0.001† | |
| Obesity | 11 (5.4%) | 378 (4.9%) | 0.741 | |
| Weight loss | 1 (0.5%) | 13 (0.2%) | 0.306† | |
| Fluid & electrolyte disorders | 27 (13.3%) | 484 (6.3%) | <0.001† | |
| Blood loss anemia | 6 (3.0%) | 43 (0.6%) | 0.002 | |
| Deficiency anemias | 11 (5.4%) | 404 (5.3%) | 0.923 | |
| Psychoses | 4 (2.0%) | 80 (1.0%) | 0.171 | |
| Depression | 9 (4.4%) | 137 (1.8%) | 0.013† | |
| Tu *** | Shock | 7 (3.5%) | 371 (4.8%) | 0.362 |
| Diabetes with complications | 7 (3.5%) | 270 (3.5%) | 0.957 | |
| Congestive Heart Failure | 53 (26.1%) | 1,644 (21.4%) | 0.109 | |
| Cancer | 0 (0.0%) | 175 (2.3%) | 0.025 | |
| Cerebrovascular disease | 8 (3.9%) | 286 (3.7%) | 0.874 | |
| Edema | 4 (2.0%) | 64 (0.8%) | 0.098 | |
| Acute renal failure | 17 (8.4%) | 302 (3.9%) | 0.002 | |
| Chronic renal failure | 13 (6.4%) | 317 (4.1%) | 0.111 | |
| Dysrhythmias | 48 (23.7%) | 1,686 (22.0%) | 0.570 | |
| Smoking ‡ | 41 (20.2%) | 750 (9.8%) | <0.001 | |
*
Substance Use Disorder Defined By Diagnostic Codes As Described In The Methods.
**
Used In MI Cohort Analysis for Adjustment Of Revascularization Outcomes.
***
Used In MI Cohort Analysis For Adjustment Of Mortality Outcomes.
†
Fisher Exact Tests Used To Calculate P-Value.
‡
Smoking Defined By ICD-9-CM Code 305.1.