Figure 5. Phenotypic response of insects to OAIP-1.

T. molitor larvae (mealworms) were monitored 5, 30, and 60 min following injection of sOAIP-1 (horizontally striped, grey, and black bars, respectively). The response was scored relative to the control as excitatory (prolonged muscle spasms), excitation to the point of paralysis (spasms so severe the insect was unable to move independently), or death/moribund (dead or, if alive, the insect was unable to right itself when turned on its back). See Table S2 for details for the scoring matrix. No dose produced a depressed state at any of the time points. Columns represent the mean ±SEM of three replicates of 10 insects for each dose.