Figure 5. Gene expression analysis of human adipocytes after incubation with BMP7, FNDC5 and irisin.
Isolated preadipocytes from human subcutaneous AT of different donors were differentiated in the presence of 50/ml BMP7, 200 ng/ml FNDC5 (Abnova), and 60 ng/ml irisin (Phoenix). Gene expression of 40 genes, related to adipocyte differentiation (A) and brite differentiation (B), was assessed by a microfluidic card TaqMan gene expression assay; n ≥4, *p<0.05, **p<0.01, ***p<0.001 vs control; n.s., not significant. White bars, control; black bars, BMP7; horizontally hatched bar, FNDC5; crossed bar, irisin. Data are presented as mean values ± SEM.