Table 1. Distribution of genotypes in ACS patients and controls.
| Gene | Polymorphism | Genotype | Frequency in ACS n(%) | Frequency in control n(%) | p value |
|---|---|---|---|---|---|
| P2RY1 | 1622 A>G | GG | 3 (0.03) | 2 (0.03) | 0.07 |
| SNP1 | AG | 34 (0.39) | 19 (0.25) | ||
| AA | 51 (0.58) | 56 (0.73) | |||
| A | 68 (0.23) | 12 (0.15) | 0.02* | ||
| G (Ref.) | 20 (0.77) | 65 (0.85) | |||
| P2RY12 | 234 T>C | TT | 21 (0.24) | 17 (0.22) | 0.06 |
| SNP2 | CT | 51 (0.58) | 56 (0.73) | ||
| CC | 16 (0.18) | 4 (0.05) | |||
| T (Ref.) | 46 (0.53) | 45 (0.58) | 0.5 | ||
| C | 42 (0.47) | 32 (0.42) | |||
| 742 T>C | TT | 4 (0.04) | 6 (0.08) | 0.26 | |
| SNP3 | CT | 11 (0.12) | 15 (0.19) | ||
| CC | 73 (0.83) | 56 (0.72) | |||
| T | 9 (0.11) | 14 (0.18) | 0.21 | ||
| C (Ref.) | 79 (0.89) | 63 (0.82) | |||
| 1622 C>T | CC | 27 (0.31) | 74 (0.96) | 0.05 | |
| SNP4 | CT | 51 (0.58) | 2 (0.03) | ||
| TT | 10 (0.11) | 1 (0.01) | |||
| C (Ref.) | 52 (0.60) | 75 (0.97) | 0.004* | ||
| T | 36 (0.40) | 2 (0.03) | |||
| 2014 C>T | CC | 61 (0.69) | 56 (0.73) | 0.49 | |
| SNP5 | CT | 25 (0.28) | 20 (0.26) | ||
| TT | 2 (0.02) | 1 (0.01) | |||
| C(Ref.) | 73 (0.84) | 66 (0.86) | 0.79 | ||
| T | 15 (0.16) | 11 (0.14) |
SNP1, G > A allele, OR= 2.1, 95% CI= 1.1-4.03; SNP4, C>T allele, OR=20.05, 95% CI= 1.0-399
significant p values are marked as ‘* ’