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Comparison of the morphological subtypes of colorectal dysplasias and cancers in C57B1/6J mice with DSS-induced colitis that are either wild-type (p53+/+) or deficient (p53+/− or p53−/−). A direct correlation exists between the number of alleles of wild-type p53 present and the percentage of polypoid colorectal lesions, while an inverse association is observed with flat lesions.
