. Author manuscript; available in PMC: 2014 Aug 13.

Published in final edited form as: Cancer Lett. 2013 Feb 13;334(1):62–68. doi: 10.1016/j.canlet.2013.02.013

Table 1.

Comparison of the characteristics of flat and polypoid colitis-associated colorectal lesions in the DSS model^*

	Strain	Treatment	Flat	Polypoid
Inflammation	SW	DSS	10×	×
Nuclear β-cat	SW/C57BL/6J	DSS	−	+
Cancers	SW	DSS	+++	+
p53 mutation	C57BL/6J (p53^−/−)	DSS	+	−
	(p53^+/+ or p53^+/−)	DSS	−	+
β-catenin mutation	C57BL/6J (p53^−/−)	DSS	+	−
	(P53^+/+, p53^+/−)	DSS	−	+
IQ	Apc^+/Min-FCCC	DSS	Increase	No change
5-ASA	SW	AOM/DSS	Decrease	Trend

DSS – dextran sulfate sodium was added to the drinking water and administered in cycles.