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. Author manuscript; available in PMC: 2014 Aug 13.
Published in final edited form as: Cancer Lett. 2013 Feb 13;334(1):62–68. doi: 10.1016/j.canlet.2013.02.013

Table 1.

Comparison of the characteristics of flat and polypoid colitis-associated colorectal lesions in the DSS model*

Strain Treatment Flat Polypoid
Inflammation SW DSS 10× ×
Nuclear β-cat SW/C57BL/6J DSS +
Cancers SW DSS +++ +
p53 mutation C57BL/6J (p53−/−) DSS +
(p53+/+ or p53+/−) DSS +
β-catenin mutation C57BL/6J (p53−/−) DSS +
(P53+/+, p53+/−) DSS +
IQ Apc+/Min-FCCC DSS Increase No change
5-ASA SW AOM/DSS Decrease Trend
*

DSS – dextran sulfate sodium was added to the drinking water and administered in cycles.