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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Neurobiol Aging. 2013 Jul 2;34(11):2604–2612. doi: 10.1016/j.neurobiolaging.2013.05.029

Fig. 6.

Fig. 6

Ctr1C RNAi significantly increased Aβ42 flies’ tolerance to oxidative stress. About 10-day old normal growing flies were treated in vials with filter paper supplemented with 5% sucrose and 20 mM paraquat. Mortality was recorded about every 8 hours and life span was measured over 45 h. Ctr1C RNAi flies (elav-Gal4>UAS-Aβ42/UAS-Ctr1C RNAi ) survived much better than control Aβ42 flies (elav-Gal4>UAS-Aβ42), with a 45.5% increase in mean life span. The two survival curves are significantly different (p<0.0001). Reported P values are from Mantel-Cox log-rank statistical analysis. The experiments were repeated at least three times.