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. 2013 Aug 12;31(27):3411–3417. doi: 10.1200/JCO.2012.46.9015

Table 3.

Effect Sizes for Outcomes With Significant Interaction Effects, Intent-to-Treat Analysis (N = 88)

Outcome Adjusted Cell Mean
Cohen d Effect Sizes, Differences in Adjusted Cell Means
A. PCO and Current Medical Treatment (n = 10) B. Control and Current Medical Treatment (n = 11) C. PCO and Not in Medical Treatment (n = 36) D. Control and Not in Medical Treatment (n = 31) PCO v Control for Participants in Treatment (A v B) PCO v Control for Participants Not in Treatment (C v D) Current Treatment v Not in Treatment for Control Group Assignees (B v D) Current Treatment v Not in Treatment for PCO Group Assignees (A v C) PCO Assignees in Treatment v Control Assignees Not in Treatment (A v D) Control Assignees in Treatment v PCO Assignees Not in Treatment (B v C)
CES-D
    Mean 10.1 20.6 9.4 10.4 1.1 0.1 1.1 0.1 0.0 1.2
    SE 2.9 3.1 1.5 1.6
    95% CI 0.3 to 1.9 −0.3 to 0.5 0.3 to 1.8 −0.6 to 0.7 −0.7 to 0.7 0.5 to 1.9
    P .006 .64 .004 .84 .91 .001
POMS-Vigor
    Mean 20.1 11.6 18.0 17.4 0.9 0.1 0.6 0.2 0.3 0.7
    SE 2.8 2.6 1.3 1.5
    95% CI 0.2 to 1.7 −0.4 to 0.5 0.0 to 1.3 −0.5 to 0.9 −0.4 to 1.0 0.1 to 1.3
    P .02 .78 .05 .52 .43 .03

NOTE. Estimates are from general linear models with measurement at 6-month assessment as dependent variable and baseline measurement, group assignment, current medical treatment status, and the interaction between group assignment and current treatment status as independent variables. Means are adjusted for other effects in the model by holding such effects constant at their marginal means. Cohen d effect sizes provide the effects on a pooled standard deviation scale. Results are based on 30 multiply imputed data sets.

Abbreviations: CES-D, Center for Epidemiologic Studies Depression Scale; PCO, Project Connect Online; POMS, Profile of Mood States.