Table 1.
The statistically significant enriched pathways of IQ-associated genes in the core dataset from different pathway databases
| Pathway | Source | Corrected P-value* |
|---|---|---|
| Neuronal system | Reactome | 4.28E-04 |
| Cocaine addiction | KEGG PATHWAY | 3.95E-03 |
| Long-term potentiation | KEGG PATHWAY | 9.04E-03 |
| Dopamine degradation | BioCyc | 1.88E-02 |
| Developmental biology | Reactome | 2.51E-02 |
| Noradrenaline and adrenaline degradation | BioCyc | 2.51E-02 |
| Adrenaline and noradrenaline biosynthesis | PANTHER | 2.76E-02 |
| Arginine and proline metabolism | KEGG PATHWAY | 3.79E-02 |
| Serotonin neurotransmitter release cycle | PID Reactome | 4.18E-02 |
| Dopamine neurotransmitter release cycle | PID Reactome | 4.18E-02 |
| Neurotransmitter release cycle | PID Reactome | 4.18E-02 |
*The corrected P-value was calculated by Fisher exact test followed by Benjamini–Hochberg multiple testing correction using the Ingenuity Pathway Tool.