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lnc-RNA molecules can function via multiple mechanisms as shown here. (I) Lnc-RNAs act as signalling molecules to other molecules that are involved in chromatin remodelling. (II) lnc-RNAs act as decoys and divert the effector molecules away from target DNA. (III) Lnc-RNAs guide the effectors to their respective target sites. (IV) Lnc-RNAs may function as a binding substratum for multiple protein molecules which act on the target gene sequence after assembly [40].
